NMN boosted aerobic endurance in trained runners

Can NMN translate into real physical performance? A six-week, randomised, double-blind, placebo-controlled study put it to the test in 48 recreationally trained runners (ages 27–50) who all followed the same structured training plan.

Runners took placebo or 300 mg, 600 mg, or 1,200 mg of NMN daily alongside their training.

Endurance improved. The medium and high doses produced significantly bigger gains in the first ventilatory threshold (VT1), a well-established marker of aerobic endurance, in a dose-dependent way versus training plus placebo.

It's a muscle effect. Maximal oxygen uptake (VO₂max) itself didn't change. The researchers concluded the endurance gains came from skeletal muscle using oxygen more efficiently, rather than from changes in the heart.

Safety. No adverse events were reported and ECG readings stayed normal across all groups.

It's a reminder that supporting NAD⁺ isn't only about how you feel at your desk, it may also show up in how your body performs.

This summary is for education only and is not medical advice. Individual results vary. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease.